A master's thesis at the faculty of Biolgy at the University of Basraha (Evaluation of Some Antimicrobial Peptides (AMPs), Secretory IgA (sIgA) and Normal Microbiota in Saliva of Covid-19 Vaccinated Individuals), and showed the researcher's thesis (Hanadi hafid abdulkareem faris) The impact COVID-19 vaccines on the immune system including biological barrier including oral microbiota which plays a crucial role in immune system regulation and overall health and secretory immunoglobulin A (sIgA), lactoferrin, and lysozymes in saliva specimens. Thesis aims to evaluate the effects of COVID-19 vaccines on adaptive immune response by measuring the level of (IgA), measuring Lysozyme and lactoferrin secretion levels and Normal microbiota as the innate immune system parameters in saliva of COVID-19 vaccinated Iraqi population groups.

and concluded The presence of a diverse range of bacterial isolates in saliva samples, with variations in species and characteristics, The measurement of sIgA, lactoferrin, and lysozyme levels in saliva samples from COVID-19 vaccine recipients and non-recipients using the ELISA technique and vaccine does not have side effect on Lactoferrin, Lysozyme, and sIgA levels in different vaccination groups. This indicates to safe use.

and recommended to : Future researchers should aim to include larger and more diverse sample populations in their studies, Investigate additional immune markers and It is essential for future researchers to correlate their findings with clinical outcomes to understand the practical implications of the vaccine-microbiota interaction.