: (The role of IL-33 and TSLP in the Pathogenicity of Asthmatic Patients in Basrah Province).

 

The University of Basrah organizes a seminar entitled (The role of IL-33 and TSLP in the

Pathogenicity of Asthmatic Patients in Basrah Province).

Media unit at the College of Science

 

The College of Science at the University of Basrah organized a seminar entitled (The role of IL-33 and TSLP in the Pathogenicity of Asthmatic Patients in Basrah Province) by the graduate student ( Mahmoud Sameer Mohamed Nuhad) The study aims to the study designed to investigate the role of IL-33 / TSLP and their receptors in the course of asthma pathogenesis related with induction of Th2 response and eosinophilia in patients with allergic asthma in Basrah province. and included significant association of eosinophils with variants (IL-33, ST2, TSLP, TSLPR and CCL24) was observed. In addition, the levels of interleukin 33 and TSLP and its receptors were high in asthmatic patients compared to control samples. IL-33 plays important roles in allergic diseases mainly by constructing the activation of various ST2-expressing cells and the production of various immunological factors. The high and significant significance of CCL24 coefficient was the clear feature of asthma patients compared to control samples and the study was recommended (Additional work should be done on (saliva and sputum) was conducted on blood samples. Other research on (saliva and sputum) for studying immune markers IL-33 and ST2 and their receptors and the study should be done on TSLP and IL-33 gene polymorphism).